Exosomes are cell-derived nanoparticles that play a pivotal role in cell-to-cell communication and are involved in a wide range of physiological processes. They have an important role in the transfer of proteins, mRNA, miRNA and other bioactive molecules between cells and regulate gene expression in recipient cells, thus influencing various molecular pathways.
One of the latest discoveries in the field of biological based therapies, exosomes are showing tremendous promise and effectiveness. When exosomes are run through an IV for systemic benefit or injected into a specific region of injury, they initiate a profound reaction that signals repair and rejuvenation to significantly reduce or eliminate pain and dysfunction.
Exosomes can be used to address conditions like osteoarthritis and/or chronic muscle and joint pain, degenerative disc disease, muscle/ligament tears, tendinitis, sports-related injuries and more. In addition, exosomes can be utilized via IV therapy to facilitate healing and recovery of numerous chronic health conditions.
What are Exosomes?
Exosomes are so-called extracellular vesicles, or small bubbles that are cell-derived nanoparticles that play a pivotal role in cell-to-cell communication and are involved in a wide range of physiological processes. They have an important role in the transfer of proteins, mRNA, miRNA and other bioactive molecules between cells and regulate gene expression in recipient cells, thus influencing various molecular pathways.
Exosomes have been heralded as the new frontier in regenerative and healing therapies. While not being cells at all, Exosomes play a vital role in the response and rejuvenation of all the cells in our body. Research is showing that the cell-to cell communication exosomes exhibit is important in maintaining the health and well-being of our cellular terrain.
Because injuries, our age, chronic disease, environmental factors and genetic disorders can interfere with the internal communication of our body’s healing process we can now use Exosomes as a key player in restoring and regulating these communication processes.
What Is Exosome Therapy?
Research has shown that if we expose the cells of an older organism to those of a younger organism we can stimulate healing and repair of the older and/or injured cells. And so, when we utilize naturally occurring exosomes and expose them to the older and/or injured cells then they will signal the healing and rejuvenation of the older cells. This healing mechanism is now being used in in our clinic for regenerative medicine procedures.
For example, a degenerative disease occurs from a continuous deterioration of cells, affecting good function of the associated tissues or organs. Our body’s stem cells are usually responsible for the rejuvenation of these deteriorating cells; however, various factors can hinder our body’s stem cells in this function and they may not be able to supply all the information needed to stimulate the repair or healing process.
And so, we can support their function with naturally occuring exosomes to provide new pieces of information to stimulate and support the healing process.
Who Can Benefit from Exosome Therapy?
Exosomes can be used to address conditions like osteoarthritis, chronic muscle and joint pain, degenerative disc/joint disease, sexual dysfunction in men and women, muscle/ligament tears, tendinitis, sports-related injuries, chronic inflammation, hair loss cases, skin aesthetics/repair, autoimmune diseases and chronic degenerative diseases. They can also be included as a part of an anti-aging regiment.
And because they are nanoparticles, exosomes can be utilized via IV therapy to facilitate systemic healing and recovery of many chronic health conditions.
How Is Exosome Therapy Performed?
Exosomes are administered as an IV treatment or site specific injection . The normal concentration of our Exosome therapy is at least 400 billion exosomes per 1ml and we have treatment options that may consist of up to 700 billion exosomes per 1ml.
In some cases, exosomes may be combined with other therapies depending on each individual case.
What Can I Expect After Exosome Therapy? Are There Any Side Effects?
Exosome therapy is performed as an outpatient procedure in our clinic. Clients should expect to leave the clinic without any down time or discomfort. In very rare instances, some clients have reported developing a mild fever or headache. However, these rare side effects never lasted more than a couple days and usually resolve within 24 hours. No long-term negative side effects have been reported.
When Can I Resume Exercise or Physical Activity?
We will discuss this based on each individual case. But we do recommend you wait at least 24 to 48 hours to do intense physical activity following a joint related treatment. And in all cases, we will have you avoid the use of anti-inflammatory drugs.
Are Exosomes Safer Than Stem Cells?
Both Exosomes and Stem Cells can have their place in a treatment protocol. And when performed correctly, treatment with exosomes and/or stem cell therapy is safe.
However, because Exosomes are not cells and our Exosomes are NOT cultured from stem cells they carry a substantially lower risk of complications than typical stem cell therapy, especially since stem cell therapy may require an invasive surgical procedure for harvesting the stem cells or you may be getting stem cells that were cultured and/or manipulated in the lab.
Also, the use of embryonic stem cells may be connected to the risk of developing tumors.
Our exosomes are sourced from full term pregnancy amniotic fluid and are naturally occurring and NOT from cultured or expanded stem cells.
Here is a link to an article many of our clients have found helpful regarding Exosomes versus stem cells.
Where Do You Get Your Exosomes?
Our Exosomes come from Organicell™. Organicell™ has a proprietary process that allows them to source Exosomes from full term pregnancy Amniotic Fluid. Organicell’s Exosomes are naturally occurring and NOT from cultured or expanded stem cells.
In addition, Organicell™ Flow is being used for IND-IRB approved clinical trials.
Can Exosomes Benefit Neurodegenerative Diseases?
Many research studies have shown that exosomes can penetrate the blood-brain barrier and stimulate neuronal differentiation, neuronal growth and suppress inflammatory processes within the brain tissue. And so, there are indications that exosomes may benefit neurodegenerative conditions and/or cognitive function.
Can Exosomes Cause Cancer?
Cancer cells that are growing in the body can produce their own exosomes that can cause cancer to grow. However, these should NOT be confused with naturally occurring exosomes sourced from amniotic fluid that we use in treatment. In fact, research is beginning to show that exosomes can actually be indicated in the treatment of some cancers as they can provide proteins to the cancer cells and stop the cancer cells replication.
How Are the Exosomes Screened For Safety?
Organicell™ Flow is procured and processed in the United States according to standards and regulations established by the United States Food & Drug Administration (FDA). Donors are screened and qualified under FDA regulation 21CRF 1271. Donor ethics and non-reactive FDA approved serological screening includes but not limited to:
- Donor consent prior to collections
- HCV (Hepatitis C Antibody)
- HBsAG (Hepatitis B Surface Antigen)
- HIV 1/11-Ab (HIV Nucleic Acid Test)
- HBcAb (Hepatitis B core Antibody)
- HCV NAt (HCV Nucleic Acid Test)